Structure of the quinone antibiotic EM5519 and the behavior of quinones in fast atom bombardment mass spectrometry.
نویسندگان
چکیده
Fast atom bombardment (FAB) mass and MS/MS spectra of a novel quinone antibiotic are presented. Their interpretation is based upon the examination of reductive behavior of model quinones in FAB solvents.
منابع مشابه
FAST ATOM BOMBARDMENT MASS SPECTROMETRY (FABMS) ANALYSIS OF AN N- TERMINAL - BLOCKED PEPTIDE
FABMS analysis of T-lb peptide before and after one cycle of Edman degradation indicated an unblocked N-terminal Thr residue for this tryptic peptide. In contrast , our data showed a molecular protonated ion, MH + for T- la peptide at 655 mass units (mu) which is 42 mu higher than the MH ion of T- 1b peptide. In addition, T- la peptide was not amenable to one cycle of manual Edman degrada...
متن کاملApplication of fast atom bombardment combined with tandem mass spectrometry to the structural elucidation of O-demethylabierixin and related polyether antibiotics.
O-Demethylabierixin, a new polyether antibiotic, was isolated from a Streptomyces spp. Its structure elucidation was carried out with fast atom bombardment mass spectrometry (FAB-MS) and fast atom bombardment mass spectrometry-mass spectrometry (FAB-MS/MS) by comparing spectral patterns with those of structurally similar polyether compounds, nigericin and abierixin. The collision-induced dissoc...
متن کاملPhytochemical investigation of abietanoid quinones: extraction, structure elucidation, toward systhesis in the laboratory
The rootes of Chinese sage, Salvia miltiorrhiza Bunge (labieteae) are used to prepare an important traditional medicine in the Chinese pharmacoepia, Dan Shen. Indeed, related members of this genus are common traditional medicines throughout the world, making Salvia species the targets of intense phytochemical investigations. The active constituents of these species have been reported to be seve...
متن کاملPositive ion fast atom bombardment mass spectrometric analysis of the molecular species of glycerophosphatidylserine.
The structure of 1,2-dipalmitoyl-sn-glycero-3-phosphoserine was analyzed by positive ion fast atom bombardment mass spectrometry and collisional activation mass-analyzed ion kinetic energy spectroscopy. The molecular weight, the polar-head group, and the fatty acid composition of this species were identified by the appearance of protonated and solvated protonated species ions, diglyceride and m...
متن کاملPhytochemical investigation of abietanoid quinones: extraction, structure elucidation, toward systhesis in the laboratory
The rootes of Chinese sage, Salvia miltiorrhiza Bunge (labieteae) are used to prepare an important traditional medicine in the Chinese pharmacoepia, Dan Shen. Indeed, related members of this genus are common traditional medicines throughout the world, making Salvia species the targets of intense phytochemical investigations. The active constituents of these species have been reported to be seve...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید
ثبت ناماگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید
ورودعنوان ژورنال:
- The Journal of antibiotics
دوره 38 1 شماره
صفحات -
تاریخ انتشار 1985